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Controlling polymersome size through microfluidic-assisted self-assembly: Enabling ‘ready to use’ formulations for biological applications

ABD

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Industry: Nanomedicine, Microfluidics
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Instrument: Vasco Kin

Industry: Nanomedicine, Microfluidics

DOI: https://doi.org/10.1016/j.ijpharm.2023.123157

Keywords: vesicles, microfluidic, nanoparticles, cryo-TEM

The self-assembly of poly(ethylene glycol)-block-poly(trimethylene carbonate) PEG-b-PTMC copolymers into vesicles, also referred as polymersomes, was evaluated by solvent displacement using microfluidic systems. Two microfluidic chips with different flow regimes (micromixer and Herringbone) were used and the impact of process conditions on vesicle formation was evaluated. (330 characters)
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With a single and continuous measurement, VASCO KIN™ gives you access to all characterization data of your reaction (size distribution evolution over time).