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Development of microfluidic-based cellulose acetate phthalate nanoparticles containing omeprazole for antiulcer activity: In vitro and in vivo evaluations

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Industry: Nanomedicine
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Instrument: Vasco

Industry: Nanomedicine

DOI: https://doi.org/10.1016/j.eurpolymj.2021.110294

Keywords: Microfluidic, Bulk, Omeprazole, In vitro, In vivo, Cellulose acetate phthalate

Omeprazole (OME)-loaded cellulose acetate phthalate nanoparticles (CAP NPs) are prepared by the use of microfluidic (MF) nanoprecipitation method for antiulcer evaluations. First, it is found that the samples synthesized by MF have smaller size (~65 nm) with lower polydispersity index (0.09) and higher surface charge (-43 ± 4.23 mV) compared to those obtained via bulk method (BM). (327 characters)
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With a single and continuous measurement, VASCO KIN™ gives you access to all characterization data of your reaction (size distribution evolution over time).