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Instrument: Vasco Flex
Industry: Nanomedicine
DOI: https://doi.org/10.2217/nnm-2019-0059
Keywords: creatine, creatine transporter deficiency, dodecyl creatine ester, drug delivery, microemulsion, nasal administration, neurotherapeutics for CTD
Creatine transporter (CrT) deficiency is an X-linked intellectual disability caused by mutations of CrT. Aim: This work focus on the preclinical development of a new therapeutic approach based on a microemulsion (ME) as drug delivery system for dodecyl creatine ester (DCE). Materials & methods: DCE-ME was prepared by titration method. (287 characters)