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Microfluidic Manufacturing of Liposomes: Development and Optimization by Design of Experiment and Machine Learning

ABD

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Industry: Microfluidics
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Instrument: Vasco Kin

Industry: Microfluidics

DOI: https://doi.org/10.1021/acsami.2c06627

Keywords: Liposomes, lipid nanoparticles, microfluidics, nanomaterial, nanomedicine, design of experiment, machine learning, artificial neural network

Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on the market. Microfluidic-based preparation methods stand up as a promising approach with high reproducibility and the ability to scale up. In this study, liposomes composed of DOPC, cholesterol, and DSPE-PEG 2000 with different molar ratios were fabricated using a microfluidic system. (323 characters)
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With a single and continuous measurement, VASCO KIN™ gives you access to all characterization data of your reaction (size distribution evolution over time).