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Instrument: Vasco Kin
Industry: Biopharmaceutics
DOI: https://doi.org/10.1186/s12989-022-00490-x
Keywords: Nanoparticles, PrPC receptor, Signaling, TNFα receptors, Aβ peptides, Neuroinfammation, Nanoneurotoxicity, Alzheimer’s disease
Epidemiological emerging evidence shows that human exposure to some nanosized materials present in the environment would contribute to the onset and/or progression of Alzheimer’s disease (AD). The cellular and molecular mechanisms whereby nanoparticles would exert some adverse effects towards neurons and take part in AD pathology are nevertheless unknown. (319)